The past decade has been very kind to kale.
After previous years of being relatively unfashionable, this leafy green has become wildly popular in recent years.
These days, it’s hard to escape hearing about the benefits of kale, and you can find kale chips, salads, and smoothies almost everywhere.
However, does it deserve all the hype?
This article examines the facts and myths behind kale’s potential benefits.
1) Kale Is a Significant Source of Vitamin K1
Kale is a substantial source of vitamin K1 (phylloquinone), and it contains 1021% of the reference daily intake (RDI) for the vitamin per 100 grams (1).
However, it is worth noting that vitamin K1’s bioavailability is relatively low.
On this note, research shows that the average bioavailability of vitamin K1 from kale in humans is 4.7% (4).
Despite this, kale still provides an impressive amount of vitamin K. Even taking the poor intestinal absorption into account, the bioavailable amount of vitamin K1 from kale would still be approximately 50% of the RDI.
As an aside, vitamin K2 (menaquinone) tends to be the most bioavailable form of vitamin K, and this is available from animal and fermented soy products such as aged cheese and natto.
2) Contains Isothiocyanates Such As Sulforaphane
Kale contains sulfur-containing compounds called glucosinolates, and these breakdown into compounds called isothiocyanates, particularly sulforaphane (5).
Alongside other cruciferous vegetables like Brussels sprouts and mustard greens, kale is one of the most significant food sources of these compounds (6).
Studies show that after absorption, these compounds are conjugated (combined) with glutathione, which is known as the body’s “master antioxidant” (7).
Regarding isothiocyanates, there is a range of studies (and speculation) investigating their potential cancer-protective properties. Until now, studies show that isothiocyanates have anti-cancer effects in laboratory animals and human cell (test tube) studies (8, 9).
Perhaps the only significant study actually in human subjects was a clinical trial of an isothiocyanate compound in 86 healthy smokers.
In this randomized controlled study, the results demonstrated that the isothiocyanate group had a 7.7% reduction in the metabolic activation of a tobacco-smoke related carcinogen (12).
3) Kale Is Extremely Nutrient-Dense
Nutrient density refers to the proportion of nutrients a food can offer compared to the typical amount of energy (calories) it provides.
In this regard, kale performs exceptionally well.
For example, just 100 grams of kale provides multiples of the RDI for vitamins A, C, and K1 (1).
Furthermore, 100 grams of kale contains these nutrient concentrations for only 50 calories.
Kale also contains every single essential mineral in varying proportions. Among these, the vegetable is especially high in manganese, calcium, and potassium.
All leafy greens offer a lot of nutritional value for very few calories, and alongside vegetables like spinach, kale is one of the best.
4) Very High In Vitamin C
Kale is one of the best dietary sources of vitamin C, and it offers approximately 200% of the RDI per 100 grams (1).
When you consider the amount of vitamin C per calorie, kale is a better source of the nutrient than some traditional vitamin C options.
|Food||Vitamin C Per 100 g||Calories Per 100 g|
|Kale||200% RDI||50 kcal|
|Lemon||128% RDI||20 kcal|
|Oranges||89% RDI||47 kcal|
|Pineapple||80% RDI||50 kcal|
As shown, kale compares very well to foods traditionally thought of as being high in the vitamin.
Vitamin C has antioxidant functions, and it is thought to help boost the immune system and protect against free radical damage (16).
5) Kale May Lower Blood Glucose Response To a Meal
Some studies suggest that kale may have a beneficial effect on postprandial blood glucose responses.
To put it another way; kale may help to suppress the blood sugar spike after eating a meal.
In a randomized controlled trial, 62 Japanese adults consumed a high-carbohydrate meal alongside either a placebo or small serving (7-14 grams) of kale.
Interestingly, the results demonstrated that the blood sugar response in the kale group was suppressed compared to placebo (17).
Other than this study, there is little research in the area, so there is limited evidence at this time.
6) Provides a Large Supply of Carotenoids (Provitamin A)
Per 100 grams, kale supplies 308% of the RDI for “vitamin A” (1).
That said, kale does not contain pre-formed vitamin A, otherwise known as retinol, and instead, it provides pro-vitamin A carotenoids.
Retinol, found in foods like liver and eggs, is also known as “pre-formed vitamin A” and our body can use it in its natural form. However, our body must first convert provitamin A (as found in kale) to retinol to use it.
Despite this, vitamin A carotenoids are still associated with numerous health benefits (20).
In particular, a systematic review and meta-analysis of metabolic syndrome and carotenoid intake analyzed the relationship over 20 years (1997 – 2007) of studies.
The analysis found that there was a significant inverse relationship between carotenoid intake and metabolic syndrome (21).
However, as always, a statistical association does not infer that carotenoids were the cause of lower metabolic syndrome.
7) Contains the Antioxidants Lutein and Zeaxanthin
In addition to the provitamin A carotenoids, kale also supplies various non-provitamin A carotenoids.
Specifically, kale provides two carotenoids that act as antioxidants in the body called lutein and zeaxanthin. Kale is one of the very best dietary sources of these two compounds (22).
Lutein and zeaxanthin are thought to have a particularly beneficial role in maintaining healthy eyesight.
8) Kale Consumption May Lower Blood Pressure
Research shows that kale may help to lower blood pressure.
In a clinical trial featuring 149 participants, daily intake of pure kale powder for eight weeks led to “significant decreases” in blood pressure (26).
The nutrient profile of kale also supports the idea that this leafy green could have positive effects on blood pressure.
For example, kale is a rich source of magnesium, potassium and vitamins C and K.
Some studies also show that vitamin C may help lower blood pressure, but the evidence is somewhat inconsistent for this (30).
In short; consuming kale could provide the right supportive nutrients to help maintain healthy blood pressure.
That said, our whole lifestyle is important, and overall diet, exercise, and sleep habits all strongly influence blood pressure.
9) Kale Contains a Variety of Polyphenols
It is easy to find claims that these compounds have anti-inflammatory, blood-pressure-lowering and anti-diabetic properties.
For now, it is probably a good idea to take claims about kale polyphenols with a pinch of salt until better research is available.
More proven options for potential benefits from polyphenols are berries, cocoa, coffee, tea, and red wine.
Potential Side Effects
Kale also has a couple of potential drawbacks regarding some of the compounds it contains.
1) Kale May Have Interactions With Warfarin Medications
Warfarin is a medication prescribed for people at risk of harmful blood clots, and it works by impairing vitamin K’s ability to help blood clot (39).
Since kale is such a significant source of vitamin K, it is a food that may potentially interfere with warfarin (40).
As such, anyone taking warfarin or other blood-thinning medications may wish to consult their doctor about consuming foods high in vitamin K.
2) Kale Contains Goitrogens
Kale is a goitrogenic food and it contains compounds called goitrogens (41).
On the negative side, research shows that these compounds may negatively affect individuals with impaired thyroid function. Goitrogens can inhibit the uptake of iodine by the thyroid, which can further impair the synthesis of thyroid hormones (42, 43).
However, only “very high intakes” are an issue, and one study showed that a 150-gram daily intake of Brussels sprouts (also high in goitrogens) for four weeks did not affect thyroid activity (44, 45).
Lastly, cooking kale will significantly reduce its concentration of goitrogens (46).
Full Nutrition Facts
For reference purposes, here is the full nutrition profile for kale per 100 grams (1).
Calories and Macronutrients
|Saturated Fat||0.1 g|
|Monounsaturated Fat||0.1 g|
|Polyunsaturated Fat||0.3 g|
|– Omega-3||180 mg|
|– Omega-6||138 mg|
|Vitamin||Amount (% DV)|
|Vitamin K1||1021 %|
|Vitamin A||308 %|
|Vitamin C||200 %|
|Vitamin B6||14 %|
|Vitamin B2||8 %|
|Vitamin B1||7 %|
|Vitamin B3||5 %|
|Vitamin B5||1 %|
|Mineral||Amount (% DV)|
Overall, kale is a nutrient-dense food with several potential health benefits, mainly related to the essential vitamins and minerals it contains.
However, some of the more exaggerated claims about kale preventing diseases need taking with a grain of salt.
In summary, kale is a great way to get some extra nutrients into our diet, but it’s not a superfood with magical benefits.
For more on vegetables, see this guide to (almost) every vegetable.